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Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

BACKGROUND: The role of TNFα in cancer is complex with both pro-tumourigenic and anti-tumourigenic roles proposed. We hypothesised that anatomical microlocalisation is critical for its function. METHODS: This study used immunohistochemistry to investigate the expression of TNFα in the tumour islets...

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Detalhes bibliográficos
Main Authors: Ohri, Chandra M, Shikotra, Aarti, Green, Ruth H, Waller, David A, Bradding, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909205/
https://ncbi.nlm.nih.gov/pubmed/20573209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-323
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