Role of the ATM-Checkpoint Kinase 2 Pathway in CDT-Mediated Apoptosis of Gingival Epithelial Cells

The cytolethal distending toxin (CDT) of the oral pathogen Aggregatibacter actinomycetemcomitans induces cell cycle arrest and apoptosis in various cell types. Western analysis, pharmacological inhibition and siRNA silencing were performed in human immortalized gingival keratinocytes (HIGK) to disse...

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Detalhes bibliográficos
Main Authors: Alaoui-El-Azher, Mounia, Mans, Jeffrey J., Baker, Henry V., Chen, Casey, Progulske-Fox, Ann, Lamont, Richard J., Handfield, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909199/
https://ncbi.nlm.nih.gov/pubmed/20668524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011714
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