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Use of Transdermal Melatonin Delivery to Improve Sleep Maintenance during Daytime
Oral melatonin can improve daytime sleep, but the hormone's short elimination half-life limits its use as a hypnotic in shift workers, jet-lag and other situations. Here we show in healthy subjects that transdermal delivery of melatonin during the daytime can elevate plasma melatonin and reduce...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909186/ https://ncbi.nlm.nih.gov/pubmed/19606092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2009.109 |
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