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Treatment with demethylating agent, 5-aza-2’-deoxycytidine enhances therapeutic HPV DNA vaccine potency

DNA vaccines have emerged as a potential alternative to current strategies to control cancer for their safety, stability and ease of preparation. We have previously demonstrated that a DNA vaccine encoding calreticulin (CRT) linked to human papillomavirus type 16 (HPV-16) E7 antigen (CRT/E7) can gen...

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Bibliografiske detaljer
Main Authors: Lu, Dan, Hoory, Talia, Monie, Archana, Wu, Annie, Wang, Mei-Cheng, Hung, Chien-Fu
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909042/
https://ncbi.nlm.nih.gov/pubmed/19481843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.02.041
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