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Higher-order Genome Organization in Human Disease
Genomes are organized into complex higher-order structures by folding of the DNA into chromatin fibers, chromosome domains, and ultimately chromosomes. The higher-order organization of genomes is functionally important for gene regulation and control of gene expression programs. Defects in how chrom...
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| Fformat: | Artigo |
| Iaith: | Inglês |
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Cold Spring Harbor Laboratory Press
2010
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908770/ https://ncbi.nlm.nih.gov/pubmed/20591991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000794 |
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