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Higher-order Genome Organization in Human Disease
Genomes are organized into complex higher-order structures by folding of the DNA into chromatin fibers, chromosome domains, and ultimately chromosomes. The higher-order organization of genomes is functionally important for gene regulation and control of gene expression programs. Defects in how chrom...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908770/ https://ncbi.nlm.nih.gov/pubmed/20591991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000794 |
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