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Motor Coordination Via Tug-Of-War Mechanism Drives Bidirectional Vesicle Transport

The microtubule motors kinesin and dynein function collectively to drive vesicular transport. High resolution tracking of vesicle motility in the cell indicates that transport is often bidirectional, characterized by frequent directional changes. However, the mechanisms coordinating the collective a...

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Main Authors: Hendricks, Adam G., Perlson, Eran, Ross, Jennifer L., Schroeder, Harry W., Tokito, Mariko, Holzbaur, Erika L. F.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908734/
https://ncbi.nlm.nih.gov/pubmed/20399099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.02.058
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