Rad3(ATR) Decorates Critical Chromosomal Domains with γH2A to Protect Genome Integrity during S-Phase in Fission Yeast

Schizosaccharomyces pombe Rad3 checkpoint kinase and its human ortholog ATR are essential for maintaining genome integrity in cells treated with genotoxins that damage DNA or arrest replication forks. Rad3 and ATR also function during unperturbed growth, although the events triggering their activati...

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Bibliographische Detailangaben
Hauptverfasser: Rozenzhak, Sophie, Mejía-Ramírez, Eva, Williams, Jessica S., Schaffer, Lana, Hammond, Jennifer A., Head, Steven R., Russell, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908685/
https://ncbi.nlm.nih.gov/pubmed/20661445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001032
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