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Rabies Virus Infection Induces Type I Interferon Production in an IPS-1 Dependent Manner While Dendritic Cell Activation Relies on IFNAR Signaling

As with many viruses, rabies virus (RABV) infection induces type I interferon (IFN) production within the infected host cells. However, RABV has evolved mechanisms by which to inhibit IFN production in order to sustain infection. Here we show that RABV infection of dendritic cells (DC) induces poten...

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Detalhes bibliográficos
Main Authors: Faul, Elizabeth J., Wanjalla, Celestine N., Suthar, Mehul S., Gale, Michael, Wirblich, Christoph, Schnell, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908622/
https://ncbi.nlm.nih.gov/pubmed/20661430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001016
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