Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement

BACKGROUND: Pichia pastoris has been recognized as an effective host for recombinant protein production. A number of studies have been reported for improving this expression system. However, its physiology and cellular metabolism still remained largely uncharacterized. Thus, it is highly desirable t...

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Main Authors: Chung, Bevan KS, Selvarasu, Suresh, Andrea, Camattari, Ryu, Jimyoung, Lee, Hyeokweon, Ahn, Jungoh, Lee, Hongweon, Lee, Dong-Yup
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908565/
https://ncbi.nlm.nih.gov/pubmed/20594333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-50
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