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A cysteine-rich metal-binding domain from rubella virus non-structural protein is essential for viral protease activity and virus replication

The protease domain within the RUBV (rubella virus) NS (non-structural) replicase proteins functions in the self-cleavage of the polyprotein precursor into the two mature proteins which form the replication complex. This domain has previously been shown to require both zinc and calcium ions for opti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHOU, Yubin, TZENG, Wen-Pin, YE, Yiming, HUANG, Yun, LI, Shunyi, CHEN, Yanyi, FREY, Teryl K., YANG, Jenny J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908387/
https://ncbi.nlm.nih.gov/pubmed/18795894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081468
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