Substrate-Enzyme Competition Attenuates Upregulated Anaplerotic Flux through Malic Enzyme in Hypertrophied Rat Heart and Restores Triacylglyceride Content: Attenuating Upregulated Anaplerosis in Hypertrophy

Recent work identifies the recruitment of alternate routes for carbohydrate oxidation, other than pyruvate dehydrogenase (PDH), in hypertrophied heart. Increased carboxylation of pyruvate via cytosolic malic enzyme (ME), producing malate, enables “anaplerotic” influx of carbon into the citric acid c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pound, Kayla M., Sorokina, Natalia, Ballal, Kalpana, Berkich, Deborah A., Fasano, Mathew, LaNoue, Kathryn F., Taegtmeyer, Heinrich, O’Donnell, J. Michael, Lewandowski, E. Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908318/
https://ncbi.nlm.nih.gov/pubmed/19213957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.189951
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados