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Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system

Nicotine is the primary component of tobacco that maintains the smoking habit and develops addiction. The adaptive changes of nicotinic acetylcholine receptors produced by repeated exposure to nicotine play a crucial role in the establishment of dependence. However, other neurochemical systems also...

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Detalhes bibliográficos
Main Authors: Berrendero, Fernando, Robledo, Patricia, Trigo, José Manuel, Martín-García, Elena, Maldonado, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908214/
https://ncbi.nlm.nih.gov/pubmed/20170672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neubiorev.2010.02.006
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