Upregulation of Id1 by Epstein-Barr Virus-encoded LMP1 confers resistance to TGFβ-mediated growth inhibition

BACKGROUND: Epstein-Barr virus (EBV)-encoded LMP1 protein is commonly expressed in nasopharyngeal carcinoma (NPC). LMP1 is a prime candidate for driving tumourigenesis given its ability to activate multiple signalling pathways and to alter the expression and activity of variety of downstream targets...

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Autores principales: Lo, Angela KF, Dawson, Christopher W, Lo, Kwok W, Yu, Yanxing, Young, Lawrence S
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908095/
https://ncbi.nlm.nih.gov/pubmed/20565867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-155
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