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Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes

BACKGROUND: The human cell cycle transcription factor FOXM1 is known to play a key role in regulating timely mitotic progression and accurate chromosomal segregation during cell division. Deregulation of FOXM1 has been linked to a majority of human cancers. We previously showed that FOXM1 was upregu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Teh, Muy-Teck, Gemenetzidis, Emilios, Chaplin, Tracy, Young, Bryan D, Philpott, Michael P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907729/
https://ncbi.nlm.nih.gov/pubmed/20187950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-45
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