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Synthesis of Glycopolymers for Microarray Applications via Ligation of Reducing Sugars to a Poly(acryloyl hydrazide) Scaffold

[Image: see text] In this paper, we report on a general synthetic strategy for the assembly of glycopolymers that capitalizes on the intrinsic reactivity of reducing glycans toward hydrazides to form stable cyclic N-glycosides. We developed a poly(acryloyl hydrazide) (PAH) scaffold to which we conju...

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Autori principali: Godula, Kamil, Bertozzi, Carolyn R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2010
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907714/
https://ncbi.nlm.nih.gov/pubmed/20608651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103009d
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