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The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants

Although there are currently 62 mutants of Cx43 (connexin43) that can cause ODDD (oculodentodigital dysplasia), only two mutants have also been reported to cause palmar plantar hyperkeratosis. To determine how mutants of Cx43 can lead to this skin disease, REKs (rat epidermal keratinocytes) were eng...

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Bibliografische gegevens
Hoofdauteurs: Churko, Jared M., Langlois, Stephanie, Pan, Xinyue, Shao, Qing, Laird, Dale W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907710/
https://ncbi.nlm.nih.gov/pubmed/20515445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100155
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