Peroxisome proliferator-activated receptors-alpha modulate dopamine cell activity through nicotinic receptors

BACKGROUND: Modulation of midbrain dopamine neurons by nicotinic acetylcholine receptors (nAChRs) plays an important role in behavior, cognition, motivation and reward. Specifically, nAChRs containing β2 subunits (β2-nAChRs) switch dopamine cells from a resting to an excited state. However, how β2-n...

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Autori principali: Melis, Miriam, Carta, Stefano, Fattore, Liana, Tolu, Stefania, Yasar, Sevil, Goldberg, Steven R., Fratta, Walter, Maskos, Uwe, Pistis, Marco
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907468/
https://ncbi.nlm.nih.gov/pubmed/20570248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.04.016
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