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Striatal dysfunction marks preexisting risk and medial prefrontal dysfunction is related to problem drinking in children of alcoholics

BACKGROUND: Parental alcoholism substantially raises risk for offspring alcoholism, an effect thought to be mediated by a dysregulation in impulse control. Adult alcoholics have alterations in the frontostriatal system involved in regulating impulsive responses. However, it remains controversial whe...

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Detalhes bibliográficos
Main Authors: Heitzeg, Mary M., Nigg, Joel T., Yau, Wai-Ying Wendy, Zucker, Robert A., Zubieta, Jon-Kar
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907458/
https://ncbi.nlm.nih.gov/pubmed/20416863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.02.020
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