The Interaction between AID and CIB1 Is Nonessential for Antibody Gene Diversification by Gene Conversion or Class Switch Recombination

Activation-induced deaminase (AID) initiates somatic hypermutation, gene conversion and class switch recombination by deaminating variable and switch region DNA cytidines to uridines. AID is predominantly cytoplasmic and must enter the nuclear compartment to initiate these distinct antibody gene div...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Demorest, Zachary L., MacDuff, Donna A., Brown, William L., Morham, Scott G., Parise, Leslie V., Harris, Reuben S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907397/
https://ncbi.nlm.nih.gov/pubmed/20652029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011660
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