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Reduced NAA-Levels in the NAWM of Patients with MS Is a Feature of Progression. A Study with Quantitative Magnetic Resonance Spectroscopy at 3 Tesla

BACKGROUND: Reduced N-acetyl-aspartate (NAA) levels in magnetic resonance spectroscopy (MRS) may visualize axonal damage even in the normal appearing white matter (NAWM). Demyelination and axonal degeneration are a hallmark in multiple sclerosis (MS). OBJECTIVE: To define the extent of axonal degene...

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Autors principals: Aboul-Enein, Fahmy, Krššák, Martin, Höftberger, Romana, Prayer, Daniela, Kristoferitsch, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907390/
https://ncbi.nlm.nih.gov/pubmed/20652023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011625
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