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Enhancement of antitumor activity of docetaxel by celecoxib in lung tumors

Our study investigates the effect of a highly selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, on the cytotoxicity of docetaxel in nude mice bearing A549 tumor xenografts and elucidates the molecular mechanisms of the antitumor effect of this combination. Female nu/nu mice, xenografted with...

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Bibliographic Details
Main Authors: Shaik, Madhu Sudhan, Chatterjee, Abhijit, Jackson, Tanise, Singh, Mandip
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907249/
https://ncbi.nlm.nih.gov/pubmed/16052515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.21325
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