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Failures in Mitochondrial tRNA(Met) and tRNA(Gln) Metabolism Caused by the Novel 4401A>G Mutation Are Involved in Essential Hypertension in a Han Chinese Family

We report here on the clinical, genetic, and molecular characterization of 1 Han Chinese family with maternally transmitted hypertension. Three of 7 matrilineal relatives in this 4-generation family exhibited the variable degree of essential hypertension at the age at onset, ranging from 35 to 60 ye...

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Detalhes bibliográficos
Main Authors: Li, Ronghua, Liu, Yuqi, Li, Zongbin, Yang, Li, Wang, Shiwen, Guan, Min-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907155/
https://ncbi.nlm.nih.gov/pubmed/19546379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.129270
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