Allopregnanolone Levels are Reduced in Temporal Cortex in Patients with Alzheimer’s Disease Compared to Cognitively Intact Control Subjects

BACKGROUND: The neurosteroid allopregnanolone has pronounced neuroprotective actions, increases myelination, and enhances neurogenesis. Evidence suggests that allopregnanolone dysregulation may play a role in the pathophysiology of Alzheimer’s disease (AD) and other neurodegenerative disorders. Our...

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Bibliografiske detaljer
Main Authors: Naylor, Jennifer C., Kilts, Jason D., Hulette, Christine M., Steffens, David C., Blazer, Dan G., Ervin, John F., Strauss, Jennifer L., Allen, Trina B., Massing, Mark W., Payne, Victoria M., Youssef, Nagy A., Shampine, Lawrence J., Marx, Christine E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907131/
https://ncbi.nlm.nih.gov/pubmed/20488256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2010.05.006
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