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Nap1 and Chz1 have separate Htz1-nuclear import and assembly functions

We analyzed the nuclear import and regulation of the yeast histone variant Htz1 (H2A.Z), and the role of histone chaperones Nap1 and Chz1 in this process. Co-purification suggested that Htz1 and H2B dimerized in the cytoplasm prior to import. Like H2B, Htz1 contained an NLS in its N-terminus that is...

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Bibliographic Details
Main Authors: Straube, Korinna, Blackwell, Jeffrey S., Pemberton, Lucy F.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2907061/
https://ncbi.nlm.nih.gov/pubmed/19929865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2009.01010.x
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