Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

Systemic lupus erythematosus (SLE) is an autoimmune disease in which patients develop autoantibodies to DNA, histones, and often to neutrophil proteins. These form immune complexes that are pathogenic and may cause lupus nephritis. In SLE patients, infections can initiate flares and are a major caus...

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Autori principali: Hakkim, Abdul, Fürnrohr, Barbara G., Amann, Kerstin, Laube, Britta, Abed, Ulrike Abu, Brinkmann, Volker, Herrmann, Martin, Voll, Reinhard E., Zychlinsky, Arturo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906830/
https://ncbi.nlm.nih.gov/pubmed/20439745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909927107
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