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Saccharomyces cerevisiae-based system for studying clustered DNA damages
DNA-damaging agents can induce clustered lesions or multiply damaged sites (MDSs) on the same or opposing DNA strands. In the latter, attempts to repair MDS can generate closely opposed single-strand break intermediates that may convert non-lethal or mutagenic base damage into double-strand breaks (...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906745/ https://ncbi.nlm.nih.gov/pubmed/20552213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00411-010-0303-3 |
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