Chemical synthesis and biological activities of 3-alkyl pyridinium polymeric analogues of marine toxins

Two new large poly-1,3-dodecylpyridinium salts, APS12 and APS12-2 of 12.5- and 14.7-kDa size, respectively, were synthesised and tested for their pore-forming and transfection capabilities in HEK 293 and undifferentiated mouse ES cells using patch-clamp recording, Ca(2+) imaging and flow cytometry....

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Main Authors: Houssen, Wael E., Lu, Zhibao, Edrada-Ebel, RuAngelie, Chatzi, Christina, Tucker, Steven J., Sepčić, Kristina, Turk, Tom, Zovko, Ana, Shen, Sanbing, Mancini, Ines, Scott, Roderick H., Jaspars, Marcel
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906715/
https://ncbi.nlm.nih.gov/pubmed/21326630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-010-0036-4
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