Role of heme oxygenase-1 in human endothelial cells – lesson from the promoter allelic variants

OBJECTIVE: Heme oxygenase-1 (HO-1) is an anti-oxidative, anti-inflammatory, and cytoprotective enzyme, which is induced in response to cellular stress. HO-1 promoter contains a (GT)n microsatellite DNA, and number of GT repeats can influence the occurrence of cardiovascular diseases. We elucidated t...

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Main Authors: Taha, Hevidar, Skrzypek, Klaudia, Guevara, Ibeth, Nigisch, Anneliese, Mustafa, Stefan, Grochot-Przeczek, Anna, Ferdek, Pawel, Was, Halina, Kotlinowski, Jerzy, Kozakowska, Magdalena, Balcerczyk, Aneta, Muchova, Lucie, Vitek, Libor, Weigel, Guenter, Dulak, Jozef, Jozkowicz, Alicja
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906705/
https://ncbi.nlm.nih.gov/pubmed/20508205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.207316
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