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Incorporation of CD40 Ligand into SHIV Virus-Like Particles (VLP) Enhances SHIV-VLP-Induced Dendritic Cell Activation and Boosts Immune Responses against HIV

Engagement of CD40 with CD40L induces dendritic cell (DC) maturation and activation, thereby promoting immune responses. The objective of this study was to investigate whether immunization with chimeric CD40L/SHIV virus-like particles (CD40L/SHIV-VLP) could enhance immune responses to SIV Gag and HI...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhang, Rongxin, Zhang, Sheng, Li, Min, Chen, Changyi, Yao, Qizhi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906648/
https://ncbi.nlm.nih.gov/pubmed/20471443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.03.079
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