Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3

Cervical carcinomas are initiated through a series of well-defined stages that rely on the expression of human papillomavirus (HPV) oncogenes. A panel of 100 small hairpin RNAs that target essential kinases in many tumor types was used to study the stepwise appearance of kinase requirements during c...

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Detalhes bibliográficos
Main Authors: Baldwin, Amy, Grueneberg, Dorre A., Hellner, Karin, Sawyer, Jacqueline, Grace, Miranda, Li, Wenliang, Harlow, Ed, Munger, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906576/
https://ncbi.nlm.nih.gov/pubmed/20616055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007462107
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