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High-Throughput Identification of Chemical Inhibitors of E. coli Group 2 Capsule Biogenesis as Anti-Virulence Agents

Rising antibiotic resistance among Escherichia coli, the leading cause of urinary tract infections (UTIs), has placed a new focus on molecular pathogenesis studies, aiming to identify new therapeutic targets. Anti-virulence agents are attractive as chemotherapeutics to attenuate an organism during d...

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Detalhes bibliográficos
Main Authors: Goller, Carlos C., Seed, Patrick C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906519/
https://ncbi.nlm.nih.gov/pubmed/20657847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011642
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