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Lon Protease Quality Control of Presecretory Proteins in Escherichia coli and Its Dependence on the SecB and DnaJ (Hsp40) Chaperones

Various environmental insults result in irreversible damage to proteins and protein complexes. To cope, cells have evolved dedicated protein quality control mechanisms involving molecular chaperones and proteases. Here, we provide both genetic and biochemical evidence that the Lon protease and the S...

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Autors principals: Sakr, Samer, Cirinesi, Anne-Marie, Ullers, Ronald S., Schwager, Françoise, Georgopoulos, Costa, Genevaux, Pierre
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906341/
https://ncbi.nlm.nih.gov/pubmed/20504766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133058
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