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A Systems Biology Approach to Dissection of the Effects of Small Bicyclic Peptidomimetics on a Panel of Saccharomyces cerevisiae Mutants

In recent years, an approach called “chemical genetics” has been adopted in drug research to discover and validate new targets and to identify and optimize leads by high throughput screening. In this work, we tested the ability of a library of small peptidomimetics to induce phenotypic effects with...

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Detalhes bibliográficos
Main Authors: Stefanini, Irene, Trabocchi, Andrea, Marchi, Emmanuela, Guarna, Antonio, Cavalieri, Duccio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906338/
https://ncbi.nlm.nih.gov/pubmed/20501664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125153
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