The Sortase A Enzyme That Attaches Proteins to the Cell Wall of Bacillus anthracis Contains an Unusual Active Site Architecture

The pathogen Bacillus anthracis uses the Sortase A (SrtA) enzyme to anchor proteins to its cell wall envelope during vegetative growth. To gain insight into the mechanism of protein attachment to the cell wall in B. anthracis we investigated the structure, backbone dynamics, and function of SrtA. Th...

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Bibliographic Details
Main Authors: Weiner, Ethan M., Robson, Scott, Marohn, Melanie, Clubb, Robert T.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906334/
https://ncbi.nlm.nih.gov/pubmed/20489200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135434
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