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Mode of Action of RNase BN/RNase Z on tRNA Precursors: RNase BN DOES NOT REMOVE THE CCA SEQUENCE FROM tRNA

RNase BN, the Escherichia coli homolog of RNase Z, was previously shown to act as both a distributive exoribonuclease and an endoribonuclease on model RNA substrates and to be inhibited by the presence of a 3′-terminal CCA sequence. Here, we examined the mode of action of RNase BN on bacteriophage a...

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Detalhes bibliográficos
Main Authors: Dutta, Tanmay, Deutscher, Murray P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906279/
https://ncbi.nlm.nih.gov/pubmed/20489203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.141101
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