High-Mobility Group Box-1 Protein Serum Levels Do Not Reflect Monocytic Function in Patients with Sepsis-Induced Immunosuppression

Background. High-mobility group box-1 (HMGB-1) protein is released during “late sepsis” by activated monocytes. We investigated whether systemic HMGB-1 levels are associated with indices of monocytic activation/function in patients with sepsis-induced immunosuppression. Methodology. 36 patients (31...

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Bibliographic Details
Main Authors: Unterwalder, Nadine, Meisel, Christian, Savvatis, Konstantinos, Hammoud, Ben, Fotopoulou, Christina, Volk, Hans-Dieter, Reinke, Petra, Schefold, Joerg C.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905954/
https://ncbi.nlm.nih.gov/pubmed/20652004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/745724
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