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Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)

The purpose of this paper is to evaluate the chronic effect of sitagliptin on metabolic profile, inflammation, and redox status in the Zucker Diabetic Fatty (ZDF) rat, an animal model of obese type 2 diabetes. Diabetic and obese ZDF (fa/fa) rats and their controls (ZDF +/+) were treated during 6 wee...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ferreira, Liliana, Teixeira-de-Lemos, Edite, Pinto, Filipa, Parada, Belmiro, Mega, Cristina, Vala, Helena, Pinto, Rui, Garrido, Patrícia, Sereno, José, Fernandes, Rosa, Santos, Paulo, Velada, Isabel, Melo, Andreia, Nunes, Sara, Teixeira, Frederico, Reis, Flávio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905949/
https://ncbi.nlm.nih.gov/pubmed/20652060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/592760
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