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Bone Damage in Rheumatoid Arthritis – Mechanistic Insights and Approaches to Prevention
In rheumatoid arthritis, cells within the inflamed synovium and pannus elaborate a variety of cytokines, including TNFα, IL-1, IL-6 and IL-17, that contribute to inflammation, and may directly impact bone. The RANKL/RANK/OPG pathway plays a critical role in regulating osteoclastogenesis in articular...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905601/ https://ncbi.nlm.nih.gov/pubmed/20510240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.rdc.2010.03.003 |
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