Saururus cernuus Lignans - Potent Small Molecule Inhibitors of Hypoxia-Inducible Factor-1

Hypoxia-inducible factor-1 (HIF-1) represents an important tumor-selective therapeutic target for solid tumors. In search of novel small molecule HIF-1 inhibitors, 5400 natural product-rich extracts from plants, marine organisms, and microbes were examined for HIF-1 inhibitory activities using a cel...

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Autors principals: Hossain, Chowdhury Faiz, Kim, Yong-Pil, Baerson, Scott R., Zhang, Lei, Bruick, Richard K., Mohammed, Kaleem A., Agarwal, Ameeta K., Nagle, Dale G., Zhou, Yu-Dong
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905542/
https://ncbi.nlm.nih.gov/pubmed/15967416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.05.191
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