Hyperglycemia Modulates Plasminogen Activator Inhibitor-1 Expression and Aortic Diameter in Experimental Aortic Aneurysm Disease

BACKGROUND: Extracellular matrix degradation is a sentinel pathologic feature of abdominal aortic aneurysm (AAA) disease. Diabetes mellitus, a negative risk factor for AAA, may impair aneurysm progression through its influence on the fibrinolytic system. We hypothesize that hyperglycemia limits AAA...

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Bibliografiske detaljer
Main Authors: Dua, Monica M., Miyama, Noriyuki, Azuma, Junya, Schultz, Geoffrey M., Sho, Mien, Morser, John, Dalman, Ronald L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905480/
https://ncbi.nlm.nih.gov/pubmed/20561659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.05.014
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