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Unraveling the mechanism of action of a new type III secretion system effector AexU from Aeromonas hydrophila

We recently characterized a T3SS effector, AexU, from a diarrheal isolate SSU of Aeromonas hydrophila, which exhibited ADP-ribosyltransferase (ADPRT) activity. Here we provided evidence that AexU also possessed GTPase-activating protein (GAP) activity, which was mainly responsible for host cell apop...

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Bibliographische Detailangaben
Hauptverfasser: Sierra, Johanna C., Suarez, Giovanni, Sha, Jian, Baze, Wallace B., Foltz, Sheri M., Chopra, Ashok K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905471/
https://ncbi.nlm.nih.gov/pubmed/20553837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.05.011
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