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Development of a Prolonged Calcium Plateau in Hippocampal Neurons in Rats Surviving Status Epilepticus Induced by the Organophosphate Diisopropylfluorophosphate

Organophosphate (OP) compounds are among the most lethal chemical weapons ever developed and are irreversible inhibitors of acetylcholinesterase. Exposure to majority of OP produces status epilepticus (SE) and severe cholinergic symptoms that if left untreated are fatal. Survivors of OP intoxication...

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Detalhes bibliográficos
Main Authors: Deshpande, Laxmikant S., Carter, Dawn S., Blair, Robert E., DeLorenzo, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905411/
https://ncbi.nlm.nih.gov/pubmed/20498005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq157
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