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Benzo[a]pyrene Increases the Nrf2 Content by Downregulating the Keap1 Message
We employed the suppressive subtractive hybridization to identify 41 up- and downregulated transcripts in Jurkat cells after benzo[a]pyrene (BaP) treatment. Among the 21 downregulated transcripts, we found that BaP suppresses the Keap1 transcript by 7.5-fold. Subsequent analyses revealed that BaP si...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905407/ https://ncbi.nlm.nih.gov/pubmed/20498004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq150 |
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