Methylmercury Induces Acute Oxidative Stress, Altering Nrf2 Protein Level in Primary Microglial Cells

The neurotoxicity of methylmercury (MeHg) is well documented in both humans and animals. MeHg causes acute and chronic damage to multiple organs, most profoundly the central nervous system (CNS). Microglial cells are derived from macrophage cell lineage, making up ∼12% of cells in the CNS, yet their...

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Detalhes bibliográficos
Main Authors: Ni, Mingwei, Li, Xin, Yin, Zhaobao, Jiang, Haiyan, Sidoryk-Węgrzynowicz, Marta, Milatovic, Dejan, Cai, Jiyang, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Neurotoxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905400/
https://ncbi.nlm.nih.gov/pubmed/20421342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq126
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