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Tumors as organs: complex tissues that interface with the entire organism

Solid tumors are not simply clones of cancer cells. Instead, they are abnormal organs composed of multiple cell types and extracellular matrix. Some aspects of tumor development resemble processes seen in developing organs, while others are more akin to tissue remodeling. Some microenvironments, par...

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Autori principali: Egeblad, Mikala, Nakasone, Elizabeth S., Werb, Zena
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905377/
https://ncbi.nlm.nih.gov/pubmed/20627072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.012
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