Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone

BACKGROUND: Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Patients who respond poorly to chemotherapy have a higher risk of metastatic disease and 5-year survival rates of only 10–20%. Therefore, identifying molecular targets that are specific for OS, or more...

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Autors principals: Endo-Munoz, L, Cumming, A, Sommerville, S, Dickinson, I, Saunders, N A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905286/
https://ncbi.nlm.nih.gov/pubmed/20551950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605723
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