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PHD2 in tumour angiogenesis

Originally identified as the enzymes responsible for catalysing the oxidation of specific, conserved proline residues within hypoxia-inducible factor-1α (HIF-1α), the additional roles for the prolyl hydroxylase domain (PHD) proteins have remained elusive. Of the four identified PHD enzymes, PHD2 is...

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Autori principali: Chan, D A, Giaccia, A J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905285/
https://ncbi.nlm.nih.gov/pubmed/20461086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605682
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