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Ryanodine modification of RyR1 retrogradely affects L-type Ca(2+) channel gating in skeletal muscle

In skeletal muscle, there is bidirectional signaling between the L-type Ca(2+) channel (1,4-dihydropyridine receptor; DHPR) and the type 1 ryanodine-sensitive Ca(2+) release channel (RyR1) of the sarcoplasmic reticulum (SR). In the case of “orthograde signalling” (i.e., excitation-contraction coupli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bannister, R. A., Beam, K. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905165/
https://ncbi.nlm.nih.gov/pubmed/19802526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-009-9190-0
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