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Implication of Sphingomyelin/Ceramide Molar Ratio on the Biological Activity of Sphingomyelinase

Sphingolipid signaling plays an important, yet not fully understood, role in diverse aspects of cellular life. Sphingomyelinase is a major enzyme in these signaling pathways, catalyzing hydrolysis of sphingomyelin to ceramide and phosphocholine. To address the related membrane dynamical structural c...

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Detalhes bibliográficos
Main Authors: Boulgaropoulos, Beate, Amenitsch, Heinz, Laggner, Peter, Pabst, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905085/
https://ncbi.nlm.nih.gov/pubmed/20643068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.028
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