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Alterations of EHD1/EHD4 Protein Levels Interfere with L1/NgCAM Endocytosis in Neurons and Disrupt Axonal Targeting

Axon growth is regulated by many proteins, including adhesion molecules, which need to be trafficked correctly to axons. The adhesion molecule L1/neuron–glia cell adhesion molecule (NgCAM) travels to axons via an endocytosis-dependent pathway (transcytosis), traversing somatodendritic endosomes. The...

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Autors principals: Yap, Chan Choo C., Lasiecka, Zofia M., Caplan, Steven, Winckler, Bettina
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905050/
https://ncbi.nlm.nih.gov/pubmed/20463227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5428-09.2010
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